ConclusionĬompared with standard postoperative dressings, NPWT significantly reduced the rate of wound infection and seroma when applied to closed surgical wounds. Methodological heterogeneity across studies led to downgrading of the quality of evidence to moderate for infection and seroma, and low for dehiscence. The numbers needed to treat were three (seroma), 17 (dehiscence) and 25 (infection). The reduction in wound dehiscence was not significant. 0♳3 to 0♸9) and seroma formation (RR 0♴8, 0♲7 to 0♸4) compared with standard care. NPWT was associated with a significant reduction in wound infection (relative risk (RR) 0♵4, 95 per cent c.i. Our aim is to assess the efficacy of an affordable, low-profile single-use NPWT (single-use NPWT) on chronic lower extremity wounds that would usually be deemed too small or superficial for traditional NPWT. Ten studies met the inclusion criteria, reporting on 1311 incisions in 1089 patients. Negative pressure wound therapy (NPWT) has been used extensively for wound bed preparation. This was a systematic review and meta-analysis of randomized clinical trials of NPWT compared with standard postoperative dressings on closed surgical incisions. The aim of this study was to assess whether NPWT reduces postoperative wound complications when applied to closed surgical incisions. The evidence base to support this intervention is limited. Currently, there is no standardized approach to wound management once an infection occurs. Negative-pressure wound therapy (NPWT) is well recognized for the management of open wounds and has been applied recently to closed surgical incisions. Sternal wound infections after cardiac surgery are infrequent yet serious complications for patients. Postoperative wound complications are common following surgical procedures.
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